JSCS
Vol 76, No. 10
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J. Serb. Chem. Soc. 76 (10) 1339–1346 (2011)
UDC
547.77/79+542.913+544.478:66–975; JSCS–4208; doi: 10.2298/JSC100921117D; Original scientific paper
A
facile catalyst and solvent-free synthesis of spiro thia heterocycles on
grinding
ANSHU
DANDIA, RUBY SINGH and ASHOK LAXKAR
Department
of Chemistry, University of Rajasthan, Jaipur-302004, India
(Received 21 September 2010, revised 31
May 2011)
An efficient and mild method for the synthesis of
spiro 1,3-oxathiolan/oxathianes in
the solid state reaction at room temperature has been described. This method is
a good option to obtain the title compounds in quantitative yields in a simple
and inexpensive way. Applying this methodology, different thia heterocycles
were synthesized.
Keywords:
spiro 1,3-oxathiolane/oxathianes;
solid-state synthesis; room temperature.
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J. Serb. Chem. Soc. 76 (10) 1347–1353 (2011)
UDC
547.755+546.723+544.4+542.913:534.8; JSCS–4209; doi: 10.2298/JSC110420120K; Original scientific paper
An ultrasound-promoted green approach for the synthesis of
3-(indol-3-yl)-3-hydroxyindolin-2-ones catalyzed by Fe(III)
ALIREZA
KHORSHIDI and KHALIL TABATABAEIAN
Department
of Chemistry, Faculty of Sciences, University of Guilan,P. O. Box 41335-1914,
Iran
(Received 20 April, revised 15 June
2011)
Ferric chloride hexahydrate was used as a recyclable
homogeneous catalyst in aqueous media for the synthesis of
3-(indol-3-yl)-3-hydroxyindolin-2-ones under sonication. It was found that the
employed conditions afford the products smoothly in good to excellent yields.
Keywords:
ultrasonic irradiation; homogeneous; catalysis; ferric chloride hexahydrate.
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2011. Cited by
J. Serb. Chem. Soc. 76 (10) 1355–1364 (2011)
UDC
547.21.024+547.857+547.367:611.4+615.252; JSCS–4210; doi: 10.2298/JSC101209041I; Original scientific paper
Antithyroid activity of some 6-(alkylsulfanyl)-9H-purines
ISMAT
FATIMA, MUNAWAR A. MUNAWAR, AFFIA TASNEEM*, SARWAT JAHAN**, MISBAHUL A. KHAN and SHAKEEL AHMED**
Institute
of Chemistry, University of the Punjab-Lahore, Pakistan
*CENUM, Mayo Hospital –Lahore, Pakistan
**Department of Animal Sciences, Quid-i-AzAM University
IslAMabad, Pakistan
(Received 13 December 2010, revised 4
February 2011)
Some alkyl and aryl derivatives of 9H-purine-6-thiol
were synthesized and evaluated in vitro
and in vivo for potential antithyroid
effects. Spectrophotometric studies demonstrated 1:1 charge transfer
complexation between iodine and these compounds with quite high values of the
formation constants. The blood assays of rats treated with these compounds
revealed significant antithyroid activity for almost all the compounds, which
was further supported by a histological study of the thyroid tissues of the
animals. These compounds are expected to provide less toxic alternative of the
existing medicines as the sulfanyl group, which is known to be a cause of
toxicity of many drugs, is blocked by alkyl/aryl substituents.
Keywords: 9H-purine-6-thiol; derivatives;
iodine; antithyroid.
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J. Serb. Chem. Soc. 76 (10) 1365–1378 (2011)
UDC 546.656+577.213.3+547.963.32:615.2:537.87;
JSCS–4211; doi: 10.2298/JSC100826121L; Original scientific paper
Mechanisms of the interaction between
Pr(DNR)3 and herring-sperm DNA
XIAOCAI LIU, XINGMING WANG and
LISHENG DING*
School
of Materials Science and Engineering, Southwest University of Science and
Technology, Mianyang 62101, China
*Chengdu Institute of Biology, Chinese Academy of
Sciences, Chengdu 610041, China
(Received 26 August, revised
8 November 2010)
Research on the interaction mechanism of drugs with DNA
is essential to understand their pharmacokinetics. The interaction between rare earth complexes Pr(DNR)3 and herring-sperm DNA was studied in Tris-HCl buffer solution
(pH 7.4) by absorption and fluorescence
spectroscopy and viscosity measurements. The results showed that the modes of
interaction between Pr(DNR)3 and herring-sperm
DNA were electrostatic and intercalation. The
binding ratio was nPr(DNA)3׃ nDNA = 5׃1 and the binding constant was K
(292 K) = 4.34×103 L mol-1. Furthermore, according to the double
reciprocal method and the thermodynAMic equation, the intercalative interaction was cooperatively driven by an enthalpy
effect and an entropy effect.
Keywords: daunorubicin; rare earth complexes; herring-sperm DNA;
acridine orange; interaction
mechanism.
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2011. Cited by
J. Serb. Chem. Soc. 76 (10) 1379–1386 (2011)
UDC
635.71:665.944.7+66.094.3–92:541.459:615.27; JSCS–4212; doi: 10.2298/JSC110102116A; Original scientific pape
In vitro assessment of the protection from oxidative stress by various
fractions of Artemisia incisa PAMp.
AZIZ-UR-REHMAN,
SEHRISH GULZAR, MUHAMMAD A. ABBASI, TAYYABA SHAHZADI, TAUHEEDA RIAZ, SABAHAT Z. SIDDIQUI and MUHAMMAD AJAIB*
Department of Chemistry, Government College University, Lahore-54000,
Pakistan
*Department of Botany, Government College University, Lahore-54000,
Pakistan
(Received 2 January, revised 18 March
2011)
The methanolic extract of Artemisia incisa PAMp. was dissolved in distilled water and
successively partitioned with n-hexane,
chloroform, ethyl acetate and n-butanol.
The antioxidant potential of all these fractions and remaining aqueous fraction
was evaluated by four methods, i.e.,
the scavenging activity of the 1,1-diphenyl-2-picrylhydrazyl
radical (DPPH), the total antioxidant activity, the ferric reducing
antioxidant power (FRAP) assay and
the ferric thiocyanate assay. In addition, the total phenolics was determined.
The obtained results
revealed that AMong the studied fractions the ethyl acetate soluble fraction
showed the most potent DPPH-radical scavenging activity with an IC50 value of
5.30±0.71 µg mL-1, which is even more effective than the standard
antioxidant butylated hydroxytoluene (BHT) (IC50 value of 12.10±0.29 µg mL-1). The ethyl
acetate fraction also showed the highest FRAP
value (3677.13±0.60 µg TE mL-1), inhibition of
lipid peroxidation (60.93±1.15 % at 500 µg mL-1) and total phenolic content (95.50±0.58
mg GAE g-1) as compared to other fractions. However, the
remaining aqueous fraction was found to possess the highest antioxidant
activity of all the fractions.
Keywords: Artemisia
incisa PAMp.; DPPH assay; total antioxidant
activity; FRAP value; total phenolics; inhibition of lipid peroxidation.
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2011. Cited by
J. Serb. Chem. Soc. 76 (10) 1387–1394 (2011)
UDC
542.9+547.571+547.551+537.311.35:546.712’722’742’562:66.022.362; JSCS–4213; doi: 10.2298/JSC110111118M; Original scientific paper
Complexes of some 3d-metals with a Schiff base derived
from 5-acetAMido-1,3,4-thiadiazole-2-sulphonAMide and their biological activity
SUMAN
MALIK, SUPARNA GHOSH and LIVIU MITU*
Department
of Chemistry, Sadhu Vaswani College, Bairagarh, Bhopal – 462030, India
*Department of Physics and Chemistry, University of
Pitesti, Pitesti – 110040, Romania
(Received 11 January, revised 29 March
2011)
Using a bidentate ligand, a Schiff base of 5-acetAMido-1,3,4-thiadiazole-2-sulphonAMide,
complexes of transition metals having the general formula ML2, where M = Mn(II), Fe(II), Ni(II) and
Cu(II), were synthesized. The complexes were characterized by elemental
analysis, molar conductivity, magnetic moment, electronic, ESR and IR
spectroscopy, and particle size analysis. The conductivity data of the
complexes suggests their non-electrolytic nature. The stability constants and
free energy change for the complexes were calculated. Spectral studies and
magnetic susceptibility measurements revealed an octahedral geometry for all the
complexes. The ligand and its complexes were screened for their fungicidal
activity against Aspergillus niger and
A. flavus.
Keywords: Schiff base; conductivity; non-electrolytic;
stability constant; fungicidal activity.
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2011. Cited by
J. Serb. Chem. Soc. 76 (10)
1395–1401 (2011)
UDC
546.28’289–3+547.313.2:541.124:537.872; JSCS–4214; doi: 10.2298/JSC100921124L; Original scientific paper
Ab
initio study of the mechanism of the formation of a
bis-heterocyclic compound containing Si and Ge by reaction of germylene
silylene (H2Ge=Si:) and ethene
XIUHUI LU, JUNFENG HAN, ZHENXIA LIAN and YONGQING LI
School
of Chemistry and Chemical Engineering, University of Jinan, Jinan, Shandong, 250022, People’s Republic of
China
(Received 21 September 2010, revised 23
March 2011)
The mechanism of the cycloaddition reaction between
singlet state germylene silylene (H2Ge=Si:) and ethene was investigated by
the CCSD(T)//MP2/6-31G* method. From the potential energy profile, it can be
predicted that the reaction has only one dominant reaction pathway. The presented rule of the dominant reaction pathway is that the [2+2] cycloaddition effect of the two reactants leads to the formation of a four-membered ring silylene with Ge
(INT1). Due to sp3 hybridization of the Si atom in four-membered ring silylene with Ge (INT1), INT1 further reacts with ethene to form a
bis-heterocyclic compound with Si and Ge (P2).
Keywords:
germylene silylene; reaction mechanism; potential energy profile.
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J. Serb. Chem. Soc. 76 (10)
1403–1410 (2011)
UDC
666.32:543.218+546–328:66.081+546.49+62–405.8; JSCS–4215; doi: 10.2298/JSC101027126P; Original scientific paper
Fractal analysis of bentonite modified
with heteropoly acid using nitrogen sorption and mercury intrusion porosimetry
SRĐAN
P. PETROVIĆ, ZORICA M. VUKOVIĆ, TATJANA B.
IChTM –
Department of Catalysis and Chemical Engineering, University of Belgrade,
Njegoševa 12, Belgrade, Serbia
*Faculty of Physical Chemistry, University of Belgrade,
Studentski trg 12–16, Belgrade, Serbia
(Received 27 October 2010, revised 9 May
2011)
Experimental adsorption isotherms were used to
evaluate the specific surface area and the surface fractal dimensions of
acid-activated bentonite sAMples modified with a heteropoly acid (HPW). The aim
of the investigations was to search for correlations between the specific
surface area and the geometric heterogeneity, as characterized by the surface
fractal dimension and the content of added acid. In addition, mercury intrusion
was employed to evaluate the porous microstructures of these materials. The
results from the Frankel–Halsey–Hill method showed that, in the p/p0 region from 0.75 to 0.96, surface fractal
dimension increased with increasing content of heteropoly acid. The results from
mercury intrusion porosimetry (MIP) data showed the generation of mesoporous
structures with important topographical modifications, indicating an increase
in the roughness (fractal geometry) of the surface of the solids as a
consequence of the modification with the heteropoly acid. By comparison, MIP is
preferable for the characterization because of its wide effective probing
range.
Keywords: heteropoly acid; bentonite; fractal geometry; mercury intrusion porosimetry.
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2011. Cited by
J. Serb. Chem. Soc. 76 (10)
1411–1425 (2011)
UDC 66.018.9:666.32+66.081:67.017; JSCS–4216; doi: 10.2298/JSC100702123M; Original scientific paper
A new type of bentonite-based non-woven
composite
ALEKSANDRA
MILUTINOVIĆ-NIKOLIĆ, JASMINA DOSTANIĆ, PREDRAG BANKOVIĆ, NATAŠA JOVIĆ-JOVIČIĆ,
SLAVENKA LUKIĆ*, BRANKO ROSIĆ** and DUŠAN JOVANOVIĆ
University
of Belgrade, Institute of Chemistry, Technology and Metallurgy, Department of
Catalysis and Chemical Engineering, Njegoševa 12, Belgrade, Serbia
*University of Belgrade, Faculty of Technology and Metallurgy, Karnegijeva 4, Belgrade, Serbia
**The Highway Institute, Kumodraška 257, Belgrade,
Serbia
(Received 27 July, revised 2 November
2010)
Sandwich-like composites based on clays and textiles
are extensively applied in various fields, including civil engineering and
environmental protection. In this paper, the synthesis of a new type of
composite with embedded bentonite particles within a non-woven polyester matrix
is presented. The synthesized composite has improved mechanical properties
compared to the corresponding non-woven matrix. Although more than two-times
thinner, the synthesized composite showed mechanical properties similar to
those of a commercial composite chosen for comparison. Sorption test results
confirmed that the contribution of the textile component to the sorption of aqueous Cu(II) ions by the composite was negligible. The
sorption of aqueous Cu(II) ions on the synthesized composite was best-fitted
using the Langmuir model. The presented study confirmed that the loss of
bentonite particles from the composite can be eliminated using the suggested
synthesis method.
Keywords: composite; bentonite; non-woven; mechanical
properties; sorption.
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2011. Cited by
J. Serb. Chem. Soc. 76 (10)
1427–1436 (2011)
UDC
54–145.2+546.19:66.081+546.831+546.82:628.1.033; JSCS–4217; doi: 10.2298/JSC101014125A; Original scientific paper
Arsenic removal from aqueous solutions by sorption onto
zirconium- and titanium-modified sorbents
IVAN ANDJELKOVIĆ, DRAGAN D.
MANOJLOVIĆ, DRAGANA DJORDJEVIć*, BILJANA DOJčINOVIć*, GORAN ROGLIć and LjUBIšA IGNJATOVIć**
Faculty of Chemistry,
University of Belgrade, P.O. Box 158, 11001 Belgrade, Serbia
*Center of Chemistry,
Institute for Chemistry, Technology and Metallurgy, University of Belgrade,
Njegoševa 12, 11000 Belgrade, Serbia
**Faculty of Physical
Chemistry, University of Belgrade, 11001 Belgrade, Serbia
(Received 7 October, 2010)
Arsenic reduction in drinking water can include treatment by adsorption,
switching to alternative water sources, or blending with water that has a lower
arsenic concentration. Commercial sorbents MTM, Greensand and BIRM (Clack
Corporation) were modified with zirconium and titanium after activation. The
modifications were performed with titanium tetrachloride and zirconium
tetrachloride. The modified sorbents were dried at different temperatures. The
sorption of arsenate and arsenite dissolved in drinking water (200 mg L-1) onto the sorbents were tested using a batch procedure.
After removal of the sorbent, the concentration of arsenic was determined by
hydride generation atomic absorption spectrometry (HG-AAS). Zirconium-modified
BIRM showed the best performance for the removal of both arsenite and arsenate.
Modification of the greensand did not affect arsenic sorption ability.
Zirconium-modified BIRM diminished the concentration of total As to below 5 μg
L-1.
Keywords: arsenic; sorption;
modified sorbent; drinking water.
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J. Serb. Chem. Soc. 76 (10)
1437–1452 (2011)
UDC 628.161.2:546.19+661.183.4:657.471; JSCS–4218; doi: 10.2298/JSC101029122J; Original scientific paper
Arsenic removal from water using low-cost adsorbents –
a comparative study
BRANISLAVA
M. JOVANOVIĆ, VESNA L. VUKAŠINOVIĆ-PEŠIĆ*, ĐORĐE N. VELJOVIĆ** and LJUBINKA V. RAJAKOVIĆ**
Department
of Hydraulic and Environmental Engineering, Faculty of Civil Engineering,
University of Belgrade, Bulevar kralja Aleksandra 73, 11000 Belgrade, Serbia
*Faculty of Metallurgy and Technology, University of
Montenegro, Cetinjski put bb, 81000 Podgorica, Montenegro
**Department of Analytical Chemistry, Faculty of
Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11 000
Belgrade, Serbia
(Received 29 October 2010, revised 7 January 2011)
Inorganic arsenic removal from water using low-cost
adsorbents is presented in this paper. Selective removal of As(III) and As(V)
from water was performed with natural materials (zeolite, bentonite, sepiolite,
pyrolusite and limonite) and industrial by-products (waste filter sand as a
water treatment residual and blast furnace slag from steel production); all
inexpensive and locally available. Kinetic and equilibrium studies were
realized using batch system techniques under conditions that are likely to
occur in real water treatment systems. The natural zeolite and the industrial
by-products were found to be good and inexpensive sorbents for arsenic while
bentonite and sepiolite clays showed little affinity towards arsenic. The
highest maximum sorption capacities were obtained for natural zeolite, 4.07 mg
As(V) g-1, and waste iron slag, 4.04 mg As(V) g-1.
Keywords: adsorption; arsenic removal; arsenic remediation; low
cost sorbents.
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J. Serb. Chem. Soc. 76 (10)
1453–1454 (2011)
Errata
(printed version only)
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Copyright &AMp; copy; SHD 2011.
October 20, 2011.
For more information contact: JSCS-info@shd.org.rs